Removal of radiocesium by Medical Treatment Schedule Using Prussian Blue and Xayexalate in Rats

INTRODUCTION Many investigators report that Prussian blue is effective on removing radiocesium from the body. However, we does not agree with the results obtained from the animal experiments, because administration methods on Prussian Blue administration used in these experiments, e.g., dose, route, initial time, resulting in superior effects are marked different from the conditions in the human application (1-6). In fact, it is well known that the Prussian Blue treatment confused in Goiania accident (7-8). It is necessary to obtain the data based on the following conditions in order to assess the effects of Prussian Blue for humans; (a) the administration should be started after intake of radiocesium, (b) the daily dose is 3 g, and (c) the administration route is by oral. The purpose of the present study is to confirm the effects of Prussian Blue and Kayexalate in rats, when it is administers by the clinical use applicable to the human treatment.